Dr. Janice Wing-hang TSANG 
曾詠恆醫生
MBBS (H.K.), MRCP (U.K.), FHKCP, FHKAM (Medicine)
Clinical Assistant Professor
E-mail:jwhtsang@hkucc.hku.hk
Background:
Dr. Janice Tsang is a specialist in Medical Oncology & Advanced Internal Medicine.
She obtained her medical degree from the University of Hong Kong in 1999 and started her career in the University Department of Medicine, Queen Mary Hospital. After obtaining her MRCP (UK), she underwent further training in Medical Oncology & Advanced Internal Medicine in the Division of Haematology, Medical Oncology & BMT in the Department of Medicine, and was the Clinical Research Fellow with Professor Ian Smith in the Breast Unit, Department of Medicine, Royal Marsden Hospital, the Institute of Cancer Research, London & Surrey during 2004-2005. She is currently also the Honorary Clinical Assistant Professor in the Department of Medicine, Queen Mary Hospital, the University of Hong Kong.
Research Interest:
My main research interest is breast oncology with particular reference to triple-negative breast cancer and therapeutics.
Breast cancer is the most common female cancer both in the world and in the Asia-pacific region. It is also the most common female cancer in Hong Kong with 1 in 20 cumulative life-time risks according to the Hong Kong Cancer Registry. There is increasing data showing that breast cancer is a heterogeneous disease which should be assessed separately in different populations, as it differs substantially between Chinese and Caucasian women. Triple-negative breast tumours which are negative for ER, PR and HER-2 neu receptors are associated with younger age at presentation, tumour of higher grade with larger size and a poorer prognosis. There is recent suggestion that the prognostic outlook of Chinese triple-negative breast cancers might be somewhat different from those in the Western population. But few studies have attempted to understand the role of ethnic factor in the triple-negative entity. Our preliminary data suggested that Hong Kong Chinese triple-negative breast cancers are associated with a more favourable outlook and might behave differently when compared to their Western counterpart.
I am also interested in psycho-oncology, in collaboration with our colleagues from the Centre for Psycho-Oncology Research and Teaching in the School of Public Health, looking at the unmet psychosocial needs of cancer patients, the impact of financial burden from the therapeutic agents on patients and their families and factors affecting patients’ decision making during their treatment journey.
My other research interests include geriatric oncology and conducting various clinical trials on solid tumours, especially phase I and phase II trials, bringing novel therapeutics to reality in the clinic.
Selected Publications:
- Chua D.T.T., Hung K.N., Lee V.H.F., Ng C.Y. and Tsang J. Validation of a prognostic scoring system for locally recurrent nasopharyngeal carcinoma treated by stereotactic radiosurgery, BMC Cancer, 2009 Apr 29;9:131.
- Chua D.T.T., Wu S.X., Lee V.H.F. and Tsang J. Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: a matched-cohort analysis, Head & Neck Oncology, 2009 May 23;1(1):13
Tsang J. Recent Medical Advances in Breast Cancer, The Hong Kong Medical Diary, 2008, 13, 21-24
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